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Aripiprazole Impurity 46

Aripiprazole Impurity 46

Product Description
CAT No.
ALN-A001027
CAS No.
519138-48-8
Mol. F.
C22H26Cl4N4 : 2(HCl)
Mol. Wt.
488.3 : 2(36.5)
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Chemical Name : Piperazine, 1,​1′-​[ethylidenebis(2,​3-​dichloro-​4,​1-​phenylene)​]​bis-​, dihydrochloride (9CI);
Smiles : CC(C1=CC=C(N2CCNCC2)C(Cl)=C1Cl)C3=CC=C(N4CCNCC4)C(Cl)=C3Cl.[2 HCl]
Inchi : InChI=1S/C9H10ClNO2/c1-13-8-4-2-3-7(5-8)11-9(12)6-10/h2-5H,6H2,1H3,(H,11,12)
Synonym : Aripiprazole Impurity;

Formulation of aripiprazole-loaded pH-modulated solid dispersions via hot-melt extrusion technology: In vitro and In vivo studies

Haley McFall1 , Sandeep Sarabu1 , Vijaykumar Shankar1 , Suresh Bandari1 , S. Narasimha Murthy1 , Karl Kolter2 , Nigel Langley3 , Dong Wuk Kim4**, Michael A. RepkanInternational Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311

Molecular determinants of the intrinsic efficacy of the antipsychotic aripiprazole

Identification of Degradation Impurities in Aripiprazole Oral Solution Using LC-MS and Development of Validated Stability Indicating Method for Assay and Content of Two Preservatives by RP-HPLC

, Michael A. Repka – International Journal of Pharmaceutics Volume 554, 10 January 2019, Pages 302-311

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