Atazanavir EP Impurity I

Product Description
CAT No.
ALN-A009013
CAS No.
NA
Mol. F.
C42H46N6O4
Mol. Wt.
698.9
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : Methyl [(2S)-1-[[(2S,3S)-3-hydroxy-1-phenyl-4-[(E)-1-[[4-(pyridin-2-yl)phenyl]methyl]-2-[[4-(pyridin-2-yl)phenyl]methylidene]hydrazin-1-yl]butan-2-yl]amino]-3,3-dimethyl-1-oxobutan-2-yl]carbamate (as per EP)
Smiles : O[C@H]([C@H](CC1=CC=CC=C1)NC([C@@H](NC(OC)=O)C(C)(C)C)=O)CN(CC2=CC=C(C3=NC=CC=C3)C=C2)/N=C/C4=CC=C(C5=CC=CC=N5)C=C4
Inchi : InChI=1S/C38H52N6O7/c1-37(2,3)31(41-35(48)50-7)33(46)40-29(22-25-14-10-9-11-15-25)30(45)24-44(43-34(47)32(38(4,5)6)42-36(49)51-8)23-26-17-19-27(20-18-26)28-16-12-13-21-39-28/h9-21,29-32,45H,22-24H2,1-8H3,(H,40,46)(H,41,48)(H,42,49)(H,43,47)/t29-,30-,31-,32-/m1/s1
Synonym : Atazanavir Benzylidenehydrazine Carbamate
Technical Data
Reference
Determination of Genotoxic impurity in Atazanavir sulphate drug substance by LC-MS
K. Geetha Bhavania , K. Bala Murali Krishnac , N. Srinivasub* , D. Ramachandranc* , N.V.V.S.S. Ramand , B. Hari Babuc*nJ Pharm Biomed Anal. 2017 Jan 5;132:156-158
Impact of monomeric vs. micellar surfactant and surfactant-polymer interactions on nucleation-induction times of atazanavir from supersaturated solutions
, D. Ramachandranc
Simultaneous Determination of Impurities of Atazanavir and Ritonavir in Tablet Dosage Form by Using Reversed-Phase Ultra Performance Liquid Chromatographic Method
, N.V.V.S.S. Ramand , B. Hari Babuc
RFQ