N-Desmethyl Azelastine

Product Description
CAT No.
ALN-A043009
CAS No.
47491-38-3
Mol. F.
C21H22ClN3O
Mol. Wt.
367.9
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 4-[(4-Chlorophenyl)methyl]-2-(hexahydro-1H-azepin-4-yl)-1(2H)-phthalazinone;Demethylazelastine;
Smiles : O=C1N(C2CCNCCC2)N=C(CC3=CC=C(Cl)C=C3)C4=CC=CC=C41
Inchi : InChI=1S/C22H24ClN3O.ClH/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16;/h2-3,6-11,18H,4-5,12-15H2,1H3;1H/t18-;/m0./s1
Technical Data
Reference
Simultaneous Estimation of Fluticasone propionate, Azelastine Hydrochloride, Phenylethyl alcohol and Benzalkonium chloride by RP-HPLC Method in Nasal spray preparations
K. Lakshmi Narasimha Rao,K. Padmaja Reddy2, K. Sudheer Babu2, K. Soloman Raju2, K. Visweswara Rao2, Jafer Vali ShaiknInt. J. Res. Pharm. Sci. Vol-1, Issue-4, 473-480, 2010
A study on forced degradation and validation of stability indicating rp-hplc method for determination of benzalkonium chloride in azelastine hydrochoride pharmaceutical ophthalmic formulation
Pratik kumar gupta, vibha chaturvedi – Asian J Pharm Clin Res, Vol 10, Issue 11, 2017, 374-382
Green Analytical Methods for the Separation of Seven Antihistamines: Application in Separation of Azelastine and Related Impurities in Nasal Solution
Lucas Maciel da Costa,1 Heitor Oliveira de Almeida Leite,1 Nájla Mohamad Kassab , 2 and Anil Kumar Singh – Hindawi International Journal of Analytical Chemistry Volume 2019, Article ID 9489723, 11 pages
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