Binimetinib Cyclized Impurity

Product Description
CAT No.
ALN-B053005
CAS No.
NA
Mol. F.
C21H23BrF2N4O4
Mol. Wt.
513.3
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Technical Data
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Product Overview
Chemical Name : 5-((4-Bromo-2-fluorophenyl)amino)-N-(2-(1-ethoxyethoxy)ethoxy)-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxamide
Smiles : O=C(C1=CC2=C(C(F)=C1NC3=C(F)C=C(Br)C=C3)N=CN2C)NOCCOC(C)OCC
Inchi : InChI=1S/C17H15BrF2N4O3/c1-24-8-21-13-7-10(17(26)23-27-5-4-25)15(14(20)16(13)24)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)
Technical Data
Reference
A validated LC-MS/MS assay for the simultaneous quantification of the FDA-approved anticancer mixture (encorafenib and binimetinib): metabolic stability estimation
By Attwa, Mohamed W.; Darwish, Hany W.; Al-Shakliah, Nasser S.; Kadi, Adnan A.nFrom Molecules (2021), 26(9), 2717
A Validated LC-MS/MS Assay for the Simultaneous Quantification of the FDA-Approved Anticancer Mixture (Encorafenib and Binimetinib): Metabolic Stability Estimation
By Attwa Mohamed W; Darwish Hany W; Al-Shakliah Nasser S; Kadi Adnan A; Attwa Mohamed W; Darwish Hany W – From Molecules (Basel, Switzerland) (2021), 26(9)
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