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Bosentan Impurity 10

Bosentan Impurity 10

Product Description
CAT No.
ALN-B017021
CAS No.
10362-14-8
Mol. F.
C10H16N2
Mol. Wt.
164.3
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RFQ
Chemical Name : 4-(Tert-butyl)benzene-1,3-diamine
Smiles : CC(C)(C(C=CC(N)=C1)=C1N)C
Inchi : InChI=1S/C36H36N2O7/c1-37-11-9-35-19-15-25(29(39)33(35)44-31-23(41-3)7-5-17(27(31)35)13-21(19)37)43-26-16-20-22-14-18-6-8-24(42-4)32-28(18)36(20,10-12-38(22)2)34(45-32)30(26)40/h5-8,15-16,21-22,33-34,39-40H,9-14H2,1-4H3/t21-,22-,33+,34+,35+,36+/m1/s1

Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist

Peter J. Harrington, Hiralal N. Khatri, Brad S. DeHoff, Martin R. Guinn, Mark A. Boehler, and Karl A. GlasernOrganic Process Research & Development 2002, 6, 120u2212124

Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist

Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 – E-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages

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