Bosentan Impurity 7

Product Description
CAT No.
ALN-B017018
CAS No.
174227-27-1
Mol. F.
C17H17N5O4
Mol. Wt.
355.4
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 2-((6-Amino-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-yl)oxy)ethan-1-ol
Smiles : OCCOC1=NC(C2=NC=CC=N2)=NC(N)=C1OC3=C(OC)C=CC=C3
Inchi : InChI=1S/C15H13N5O3/c1-22-9-5-2-3-6-10(9)23-11-12(16)19-14(20-15(11)21)13-17-7-4-8-18-13/h2-8H,1H3,(H3,16,19,20,21)
Technical Data
Reference
Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist
Peter J. Harrington, Hiralal N. Khatri, Brad S. DeHoff, Martin R. Guinn, Mark A. Boehler, and Karl A. GlasernOrganic Process Research & Development 2002, 6, 120u2212124
Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist
Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 – E-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages
Development and validation of a stability indicating analytical method for the related substances of Bosentan drug substance by HPLC
Mubeen Ahmad Khan, Sukumar Sinha, Mangesh Todkar, Vikas Parashar, K. Swamy Reddy – Am. J. Sci. Ind. Res., 2012, 3(2): 69-80
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