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Bosentan Impurity 8

Bosentan Impurity 8

Product Description
CAT No.
ALN-B017019
CAS No.
157415-46-8
Mol. F.
C26H27N5O5S
Mol. Wt.
521.6
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RFQ
Chemical Name : 4-(Tert-butyl)-N-(6-methoxy-5-(2-methoxyphenoxy)-[2,2′-bipyrimidin]-4-yl)benzenesulfonamide
Smiles : COC1=CC=CC=C1OC2=C(OC)N=C(C3=NC=CC=N3)N=C2NS(C4=CC=C(C(C)(C)C)C=C4)(=O)=O
Inchi : InChI=1S/C17H17N5O4/c1-24-11-5-2-3-6-12(11)26-13-14(18)21-16(15-19-7-4-8-20-15)22-17(13)25-10-9-23/h2-8,23H,9-10H2,1H3,(H2,18,21,22)

Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist

Peter J. Harrington, Hiralal N. Khatri, Brad S. DeHoff, Martin R. Guinn, Mark A. Boehler, and Karl A. GlasernOrganic Process Research & Development 2002, 6, 120u2212124

Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist

Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 – E-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages

Development and validation of a stability indicating analytical method for the related substances of Bosentan drug substance by HPLC

Mubeen Ahmad Khan, Sukumar Sinha, Mangesh Todkar, Vikas Parashar, K. Swamy Reddy – Am. J. Sci. Ind. Res., 2012, 3(2): 69-80

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