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Bosentan O-Desmethyl Impurity

Bosentan O-Desmethyl Impurity

Product Description
CAT No.
ALN-B017009
CAS No.
253688-61-8
Mol. F.
C26H27N5O6S
Mol. Wt.
537.6
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RFQ
Chemical Name : 4-(Tert-butyl)-N-(6-(2-hydroxyethoxy)-5-(2-hydroxyphenoxy)-[2,2′-bipyrimidin]-4-yl)benzenesulfonamide
Smiles : O=[S](NC1=NC(C2=NC=CC=N2)=NC(OCCO)=C1OC(C=CC=C3)=C3O)(C4=CC=C(C(C)(C)C)C=C4)=O
Synonym : O-Desmethyl Bosentan

Research and Development of a Second-Generation Process for Bosentan, an Endothelin Receptor Antagonist

Peter J. Harrington, Hiralal N. Khatri, Brad S. DeHoff, Martin R. Guinn, Mark A. Boehler, and Karl A. GlasernOrganic Process Research & Development 2002, 6, 120u2212124

Stability-Indicating Gradient RP-LC Method for the Determination of Process and Degradation Impurities in Bosentan Monohydrate: An Endothelin Receptor Antagonist

Sanjay A. Jadhav,1 Shashikant B. Landge,1 Sonali L. Jadhav,1 Navanath C. Niphade,1 Saroj R. Bembalkar,2 and Vijayavitthal T. Mathad1 – E-Hindawi Access to Research Chromatography Research International Volume 2011, Article ID 929876, 9 pages

Development and validation of a stability indicating analytical method for the related substances of Bosentan drug substance by HPLC

Mubeen Ahmad Khan, Sukumar Sinha, Mangesh Todkar, Vikas Parashar, K. Swamy Reddy – Am. J. Sci. Ind. Res., 2012, 3(2): 69-80

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