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Brimonidine EP Impurity G (TFA Salt)

Brimonidine EP Impurity G (TFA Salt)

Product Description
CAT No.
ALN-B026008
CAS No.
1391054-10-6
Mol. F.
C11H12BrN5O : C2HF3O2
Mol. Wt.
310.2 : 114.0
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RFQ
Chemical Name : 1-(2-Aminoethyl)-3-(5-bromoquinoxalin-6-yl)urea trifluoroacetic acid salt ;
Smiles : O=C(NC1=CC=C2N=CC=NC2=C1Br)NCCN.O=C(O)C(F)(F)F
Inchi : InChI=1S/C11H8BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-6H,(H2,15,16,17)

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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