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Brimonidine Impurity 11

Brimonidine Impurity 11

Product Description
CAT No.
ALN-B026039
CAS No.
NA
Mol. F.
C15H14BrN5O5
Mol. Wt.
424.2
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RFQ
Chemical Name : 2-((5-Bromoquinoxalin-6-yl)(4,5-dihydro-1H-imidazol-2-yl)amino)-3-hydroxysuccinic acid
Smiles : O=C(O)C(C(C(O)=O)O)N(C1=NCCN1)C2=C(Br)C3=NC=CN=C3C=C2
Inchi : InChI=1S/C24H23FO4S/c1-14-2-3-16(21-12-20(27)24(28)22(13-26)29-21)10-17(14)11-19-8-9-23(30-19)15-4-6-18(25)7-5-15/h2-10,12,20,22,24,26-28H,11,13H2,1H3/t20-,22-,24+/m1/s1

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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