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Brimonidine Impurity 12

Brimonidine Impurity 12

Product Description
CAT No.
ALN-B026040
CAS No.
NA
Mol. F.
C15H12BrN5O4
Mol. Wt.
406.2
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RFQ
Chemical Name : 2-((5-Bromoquinoxalin-6-yl)(4,5-dihydro-1H-imidazol-2-yl)amino)maleic acid
Smiles : O=C(O)/C(N(C1=NCCN1)C2=C(Br)C3=NC=CN=C3C=C2)=C\C(O)=O
Inchi : InChI=1/C15H14BrN5O5/c16-9-8(2-1-7-10(9)18-4-3-17-7)21(15-19-5-6-20-15)11(13(23)24)12(22)14(25)26/h1-4,11-12,22H,5-6H2,(H,19,20)(H,23,24)(H,25,26)

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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