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Brimonidine Impurity 13

Brimonidine Impurity 13

Product Description
CAT No.
ALN-B026041
CAS No.
934548-66-0
Mol. F.
C15H12BrN5O3
Mol. Wt.
390.2
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RFQ
Chemical Name : 8-(5-Bromoquinoxalin-6-yl)-7-oxo-2,3,5,6,7,8-hexahydroimidazo[1,2-a]pyrimidine-5-carboxylic acid
Smiles : BrC1=C(N2C3=NCCN3C(C(O)=O)CC2=O)C=CC4=NC=CN=C41
Inchi : InChI=1S/C15H12BrN5O4/c16-12-9(2-1-8-13(12)18-4-3-17-8)21(15-19-5-6-20-15)10(14(24)25)7-11(22)23/h1-4,7H,5-6H2,(H,19,20)(H,22,23)(H,24,25)/b10-7+

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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