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Brimonidine Impurity 14

Brimonidine Impurity 14

Product Description
CAT No.
ALN-B026042
CAS No.
NA
Mol. F.
C15H10BrN5O3
Mol. Wt.
388.2
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RFQ
Chemical Name : 8-(5-Bromoquinoxalin-6-yl)-5-oxo-2,3,5,8-tetrahydroimidazo[1,2-a]pyrimidine-7-carboxylic acid
Smiles : O=C(O)C(N(C1=NCCN12)C(C=C3)=C(Br)C4=C3N=CC=N4)=CC2=O
Inchi : InChI=1/C15H12BrN5O3/c16-12-9(2-1-8-13(12)18-4-3-17-8)21-11(22)7-10(14(23)24)20-6-5-19-15(20)21/h1-4,10H,5-7H2,(H,23,24)

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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