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Brimonidine Impurity 21

Brimonidine Impurity 21

Product Description
CAT No.
ALN-B026051
CAS No.
NA
Mol. F.
C15H16BrN5O5
Mol. Wt.
426.2
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RFQ
Chemical Name : 2-((5-Bromoquinoxalin-6-yl)(imidazolidin-2-yl)amino)-3-hydroxysuccinic acid
Smiles : BrC1=C(N=CC=N2)C2=CC=C1N(C(C(O)=O)C(C(O)=O)O)C3NCCN3

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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