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Brimonidine Impurity 3

Brimonidine Impurity 3

Product Description
CAT No.
ALN-B026025
CAS No.
NA
Mol. F.
C15H12BrN5O3
Mol. Wt.
390.2
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RFQ
Chemical Name : (E)-4-(2-((5-Bromoquinoxalin-6-yl)amino)-4,5-dihydro-1H-imidazol-1-yl)-4-oxobut-2-enoic acid
Smiles : BrC1=C(N=CC=N2)C2=CC=C1NC3=NCCN3C(/C=C/C(O)=O)=O
Inchi : InChI=1S/C20H34F2O5/c1-2-3-12-20(21,22)18(25)11-10-15-14(16(23)13-17(15)24)8-6-4-5-7-9-19(26)27/h14-15,17-18,24-25H,2-13H2,1H3,(H,26,27)/t14-,15-,17-,18?/m1/s1

Sustained reduction of intraocular pressure by supraciliary delivery of brimonidine-loaded poly(lactic acid) microspheres for the treatment of glaucoma

B.Chianga1Y.C.Kimb1A.C.Dotyc12H.E.GrossniklausdS.P.SchwendemancM.R.PrausnitznJournal of Controlled Release Volume 228, 28 April 2016, Pages 48-57

Sustained release of brimonidine from a new composite drug delivery system for treatment of glaucoma

Jianguo Sun, Yuan Lei, Zhaoxing Dai∥, Xi Liu, Taomin Huang, Jihong Wu, Zhi Ping XOrcid, and Xinghuai Sun – ACS Appl. Mater. Interfaces 2017, 9, 9, 7990–7999

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems

Jianguo Sun, Xiuwen Zhang & Taomin Huang – Chemistry Central Journal volume 11, Article number: 62 (2017)

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