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Daclatasvir Nitroso Impurity 2

Daclatasvir Nitroso Impurity 2

Product Description
CAT No.
ALN-D036039
CAS No.
NA
Mol. F.
C40H49N9O7
Mol. Wt.
767.9
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RFQ
Chemical Name : Methyl ((S)-1-((S)-2-(5-(4′-(2-((S)-1-((methoxycarbonyl)-L-valyl)pyrrolidin-2-yl)-1-nitroso-1H-imidazol-5-yl)-[1,1′-biphenyl]-4-yl)-1H-imidazol-2-yl)pyrrolidin-1-yl)-3-methyl-1-oxobutan-2-yl)carbamate
Smiles : O=C([C@@H](NC(OC)=O)C(C)C)N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C5=CN=C([C@@H]6CCCN6C([C@@H](NC(OC)=O)C(C)C)=O)N5N=O)C=C4
Inchi : InChI=1S/C40H48N10O8/c1-23(2)33(43-39(53)57-5)37(51)47-19-7-9-29(47)35-41-21-31(49(35)45-55)27-15-11-25(12-16-27)26-13-17-28(18-14-26)32-22-42-36(50(32)46-56)30-10-8-20-48(30)38(52)34(24(3)4)44-40(54)58-6/h11-18,21-24,29-30,33-34H,7-10,19-20H2,1-6H3,(H,43,53)(H,44,54)/t29-,30-,33-,34-/m0/s1

A validated stability-indicating reverse-phase high-performance liquid chromatography method for daclatasvir, identification and characterization of degradation products using LC-ESI-QTOF-MS

By Warghade, Snehal V.; Bothara, Kailash G.nFrom Asian Journal of Pharmaceutical and Clinical Research (2019), 12(5), 302-308

Development and validation of HPLC fluorescence and UPLC/DAD stability-indicating methods for determination of hepatitis C antiviral agent daclatasvir

By Kamal, Andra H.; Ismail, Nahla S.; Mabroijk, Mokhtar M.; Bebawy, Lories I.; Mekky, Mai A. – From Journal of AOAC International (2019), 102(4), 1125-1131

A stability-indicating UPLC method for the determination of potential impurities and its mass by a new QDa mass detector in daclatasvir drug used to treat hepatitis C infection

By Jagadabi, Varaprasad; Kumar, P. V. Nagendra; Mahesh, Kasthuri; Pamidi, Srinivasu; Ramaprasad, L. A.; Nagaraju, D. – From Journal of Chromatographic Science (2019), 57(1), 44-53

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