Diltiazem EP Impurity E
 
		Product Description
CAT No.
				
									ALN-D029006								
				CAS No.
				
									42399-49-5								
				Mol. F.
				
									C16H15NO3S								
				Mol. Wt.
				
									301.4								
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							Product Overview
			
						
									Chemical Name : (2S,3S)-3-Hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-1,5-benzothiazepin-4(5H)-one ;								
				
									Smiles : O=C1[C@H](O)[C@H](C2=CC=C(OC)C=C2)SC3=CC=CC=C3N1								
				
									Inchi : InChI=1S/C21H24N2O4S.ClH/c1-14(24)27-19-20(15-8-10-16(26-3)11-9-15)28-18-7-5-4-6-17(18)23(21(19)25)13-12-22-2;/h4-11,19-20,22H,12-13H2,1-3H3;1H/t19-,20+;/m1./s1								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Identification of Diltiazem Impurities/Artifacts during the Analyses of Illicit Cocaine Exhibits Containing Diltiazem
									John F. Casale,1,* Pauline M. Orlando,2 Valerie L. Colley,1 and Patrick A. HaysnMicrogram Journal, Volume 6, Numbers 3-4 (July – December, 2008)								
				Validated gradient stability indicating HPLC method for determining Diltiazem Hydrochloride and related substances in bulk drug and novel tablet formulation
									 Pauline M. Orlando,2 Valerie L. Colley,1 and Patrick A. Hays – Microgram Journal, Volume 6, Numbers 3-4 (July – December, 2008) 								
				Analytical Characterization of two new related impurities of Diltiazem by High Resolution Mass spectrometry and NMR techniques
									Vivekanand A. ChatpalliwarPawan K. PorwalNeeraj Upmanyu – Journal of Pharmaceutical Analysis Volume 2, Issue 3, June 2012, Pages 226-237 								
				
							
							
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