Diphenhydramine EP Impurity A

Product Description
CAT No.
ALN-D054002
CAS No.
53499-40-4
Mol. F.
C16H19NO : HCl
Mol. Wt.
241.3 : 36.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 2-(diphenylmethoxy)-N-methylethanamin hydrochloride
Smiles : CNCCOC(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Inchi : InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
Synonym : Diphenhydramine USP Related Compound A ; N-Desmethyl diphenhydramine hydrochloride
Technical Data
Reference
Control of impurities in diphenhydramine hydrochloride by an ion-pairing, reverse-phase liquid chromatographic method
L. Henderson, J. H. McB. Miller and G. G. SkellernnJournal of Pharmacy and Pharmacology, JPP 2001, 53: 323u2013331.
Selective determination of dimenhydrinate in presence of six of its related substances and potential impurities using a direct GC/MS method
Tarek S.Belal, Karim M.Abdel-Hay, C. RandallClark – Journal of Advanced Research Volume 7, Issue 1, January 2016, Pages 53-58
Simultaneous estimation of dimenhydrinate, cinnarizine and their toxic impurities benzophenone and diphenylmethylpiperazine; in silico toxicity profiling of impurities
Nada S. Abdelwahab, ORCID logo a\xa0\xa0 Fadwa H. Edrees,b\xa0\xa0 Mohammed T. Alsaadi,cd\xa0\xa0 Noha H. Aminc\xa0 and\xa0 Ahmed S. Saad – RSC Adv., 2020, 10, 37439–37448.
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