Duloxetine EP Impurity F (oxalate salt)

Product Description
CAT No.
ALN-D001007
CAS No.
2379325-42-3
Mol. F.
C18H19NOS : C2H2O4
Mol. Wt.
297.4 : 90.0
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : (3S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-3-yl)propan-1-amine oxalate ;
Smiles : CNCC[C@H](OC1=C2C=CC=CC2=CC=C1)C3=CSC=C3.O=C(O)C(O)=O
Inchi : InChI=1S/C18H19NOS/c1-19-11-10-15(17-7-4-12-21-17)16-9-8-13-5-2-3-6-14(13)18(16)20/h2-9,12,15,19-20H,10-11H2,1H3/t15-/m1/s1
Synonym : Duloxetine USP Related Compound F ; Duloxetine 3-Thiophene Isomer
Technical Data
Reference
Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate
P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W BaertschinJ Pharm Sci. 1998 Jan;87(1):81-5.
Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC
Dantu Durga Rao1,
Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules
, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti – Journal of Chromatographic Science, Vol. 48, November/December 2010
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