Duloxetine Hydrochloride

Product Description
CAT No.
ALN-D001001
CAS No.
136434-34-9
Mol. F.
C18H19NOS : HCl
Mol. Wt.
297.4 : 36.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : (γS)-N-Methyl-γ-(1-naphthalenyloxy)-2-thiophenepropanamine Hydrochloride ;
Smiles : CNCC[C@H](OC1=C2C=CC=CC2=CC=C1)C3=CC=CS3.Cl
Inchi : InChI=1S/C18H19NOS.ClH/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16;/h2-10,13,17,19H,11-12H2,1H3;1H/t17-;/m1./s1
Technical Data
Reference
Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate
P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W BaertschinJ Pharm Sci. 1998 Jan;87(1):81-5.
Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC
Dantu Durga Rao1,
Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules
, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti – Journal of Chromatographic Science, Vol. 48, November/December 2010
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