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Duloxetine N-Methyl (R)-Isomer

Duloxetine N-Methyl (R)-Isomer

Product Description
CAT No.
ALN-D001013
CAS No.
932013-45-1
Mol. F.
C19H21NOS : C2H2O4
Mol. Wt.
311.4 : 90.0
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Chemical Name : (R)-(+)-N,N-Dimethyl-3-(1-naphthoxy)-3-(2-thienyl)-1-propylamine oxalate ;
Smiles : O=C(O)C(O)=O.CN(C)CC[C@H](C1=CC=CS1)OC2=C3C(C=CC=C3)=CC=C2
Inchi : InChI=1S/C17H17NOS.C2H2O4/c18-11-10-16(17-9-4-12-20-17)19-15-8-3-6-13-5-1-2-7-14(13)15;3-1(4)2(5)6/h1-9,12,16H,10-11,18H2;(H,3,4)(H,5,6)/t16-;/m0./s1
Synonym : Duloxetine N-Methyl (R)-Isomer ; N-Methyl (R)-Duloxetine Oxalate

Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate

P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W BaertschinJ Pharm Sci. 1998 Jan;87(1):81-5.

Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC

Dantu Durga Rao1,

Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules

, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti – Journal of Chromatographic Science, Vol. 48, November/December 2010

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