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Duloxetine S-Hydroxy Impurity

Duloxetine S-Hydroxy Impurity

Product Description
CAT No.
ALN-D001010
CAS No.
132335-44-5
Mol. F.
C9H15NOS
Mol. Wt.
185.3
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RFQ
Chemical Name : (S)-(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl) propanamine ;
Smiles : O[C@H](C1=CC=CS1)CCN(C)C
Inchi : InChI=1S/C22H23NO4S/c1-23(21(24)11-12-22(25)26)14-13-19(20-10-5-15-28-20)27-18-9-4-7-16-6-2-3-8-17(16)18/h2-10,15,19H,11-14H2,1H3,(H,25,26)/t19-/m0/s1
Synonym : Duloxetine Hydroxy Impurity

Characterization of impurities formed by interaction of duloxetine HCl with enteric polymers hydroxypropyl methylcellulose acetate succinate and hydroxypropyl methylcellulose phthalate

P J Jansen 1, P L Oren, C A Kemp, S R Maple, S W BaertschinJ Pharm Sci. 1998 Jan;87(1):81-5.

Analysis of Duloxetine Hydrochloride and Its Related Compounds in Pharmaceutical Dosage Forms and In Vitro Dissolution Studies by Stability Indicating UPLC

Dantu Durga Rao1,

Development and validation of a stability indicating rp-lc method for the estimation of process related impurities and degradation products of duloxetine hydrochloride and phthalic acid in duloxetine hydrochloride delayed release capsules

, Shakil S. Sait1, A. Malleswara Reddy1, Dinesh Chakole1, Y. Ramakoti Reddy2, and K. Mukkanti – Journal of Chromatographic Science, Vol. 48, November/December 2010

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