Effavirenz Impurity 4

Product Description
CAT No.
ALN-E003024
CAS No.
173676-60-3
Mol. F.
C21H19ClF3NO2
Mol. Wt.
409.8
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : (S)-2-(5-Chloro-2-((4-methoxybenzyl)amino)phenyl)-4-cyclopropyl-1,1,1-trifluorobut-3-yn-2-ol
Smiles : O[C@](C(F)(F)F)(C(C=C(Cl)C=C1)=C1NCC2=CC=C(OC)C=C2)C#CC3CC3
Inchi : InChI=1S/C21H17ClF3NO2/c1-27-16-7-4-14(5-8-16)19-26-18-9-6-15(22)12-17(18)20(28-19,21(23,24)25)11-10-13-2-3-13/h4-9,12-13,19,26H,2-3H2,1H3/t19?,20-/m0/s1
Technical Data
Reference
Development and validation of a HPLC analytical assay method for efavirenz tablets: a medicine for HIV infections
Osnir de Su00e1 Viana1 , Flu00e1via Patru00edcia Morais Medeiros2 , Severino Grangeiro-Ju00fanior2 , Miracy Muniz Albuquerque1 , Mu00f4nica Felts La Roca Soares1-3, Josu00e9 Lamartine Soares-Sobrinho1-3, Lariza Darlene Santos Alves1 , Larissa Arau00fajo Rolim1 , Keyla Emanuelle Ramos da Silva1 , Pedro Josu00e9 Rolim-NetonBraz. J. Pharm. Sci. vol.47 no.1 Su00e3o Paulo Jan./Mar. 2011
Investigation of the solvent-dependent photolysis of a nonnucleoside reverse-transcriptase inhibitor, antiviral agent efavirenz
Maryam A Jordaan and Michael Shapi – Antiviral Chemistry and Chemotherapy 2017: 1–11
Method Development and Validation for Related Impurities of Efavirenz by RP-HPLC Method
Desaraju Bhargavi, Bhukya Babu Rao, Gangarapu Kiran, Thumma Gouthami & Vasudha Bakshi – TACL 7 (5) 2017 pp 737 – 747
RFQ