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Enatiomer of Efinaconazole

Enatiomer of Efinaconazole

Product Description
CAT No.
ALN-E027002
CAS No.
164650-45-7
Mol. F.
C18H22F2N4O
Mol. Wt.
348.4
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Chemical Name : (2S,3S)-2-(2,4-Difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Smiles : C[C@H](N1CCC(CC1)=C)[C@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3
Inchi : InChI=1S/C18H22F2N4O/c1-13-5-7-23(8-6-13)14(2)18(25,10-24-12-21-11-22-24)16-4-3-15(19)9-17(16)20/h3-4,9,11-12,14,25H,1,5-8,10H2,2H3/t14-,18-/m1/s1
Synonym : Efinaconazole SS isomer,

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A Facile Epoxide Aminolysis Promoted by (t-BuO)2Mg and Its Application to the Synthesis of Efinaconazole

Fuqiang Zhu, Yuanchao Xie, Jian Zhang, Guanghui Tian, Hongjian Qin, Xiaojun Yang, Tianwen Hu, Yang He, Haji Akber Aisa, and Jingshan Shen – Org. Process Res. Dev. 2018, 22, 5, 625–632

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