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Enzalutamide Impurity 11

Enzalutamide Impurity 11

Product Description
CAT No.
ALN-E015027
CAS No.
NA
Mol. F.
C20H16FN3O3S
Mol. Wt.
397.4
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RFQ
Chemical Name : 2-Fluoro-4-(3-(4-isocyano-3-methylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)benzoic acid
Smiles : CC1=C([N+]#[C-])C=CC(N2C(C(C)(C)N(C3=CC(F)=C(C(O)=O)C=C3)C2=S)=O)=C1
Inchi : InChI=1S/H3O3P/c1-4(2)3/h1-3H

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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