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Enzalutamide Impurity 13

Enzalutamide Impurity 13

Product Description
CAT No.
ALN-E015029
CAS No.
1487515-37-6
Mol. F.
C10H7F3N2O2
Mol. Wt.
244.2
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Chemical Name : Methyl (4-cyano-3-(trifluoromethyl)phenyl)carbamate
Smiles : FC(F)(C(C=C(NC(OC)=O)C=C1)=C1C#N)F
Inchi : InChI=1S/C9H10N2O2S/c1-14(12,13)11-9-4-2-8(3-5-9)6-7-10/h2-5,11H,6H2,1H3

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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