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Enzalutamide Impurity 14

Enzalutamide Impurity 14

Product Description
CAT No.
ALN-E015030
CAS No.
1332524-01-2
Mol. F.
C13H17FN2O3
Mol. Wt.
268.3
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RFQ
Chemical Name : Methyl 2-(3fluoro-4-(Methylcarbamoyl ) Phenylamino)-2-methylpropanoate
Smiles : CC(C)(NC1=CC=C(C(NC)=O)C(F)=C1)C(OC)=O
Inchi : InChI=1S/C18H18ClN5O4/c1-9-2-4-10(5-3-9)17(26)28-11-6-13(27-12(11)7-25)24-8-21-14-15(20)22-18(19)23-16(14)24/h2-5,8,11-13,25H,6-7H2,1H3,(H2,20,22,23)/t11-,12+,13+/m0/s1

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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