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Enzalutamide Impurity 19

Enzalutamide Impurity 19

Product Description
CAT No.
ALN-E015036
CAS No.
NA
Mol. F.
C22H19F4N3O3
Mol. Wt.
449.4
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RFQ
Chemical Name : 4-(4-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-3,3-dimethyl-1,4-dioxobutan-2-yl)-2-fluoro-N-methylbenzamide
Smiles : O=C(NC)C1=CC=C(C(C(C)(C)C(NC2=CC=C(C#N)C(C(F)(F)F)=C2)=O)C=O)C=C1F
Inchi : InChI=1S/C22H30FN3O6S.C6H15N/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;1-5(2)7-6(3)4/h5-8,13,16-17,27-28H,9-12H2,1-4H3,(H,29,30);5-7H,1-4H3/t16-,17+;/m0./s1

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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