Enzalutamide Impurity 36

Product Description
CAT No.
ALN-E015054
CAS No.
2341510-75-4
Mol. F.
C10H7F3N2S2
Mol. Wt.
276.3
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Technical Data
Reference
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Product Overview
Chemical Name : Methyl (4-cyano-3-(trifluoromethyl)phenyl)carbamodithioate
Smiles : FC(F)(C(C=C(NC(SC)=S)C=C1)=C1C#N)F
Inchi : InChI=1S/C28H51NO5/c1-6-8-9-10-11-12-13-14-15-16-23(33-28(32)25(29-20-30)17-21(3)4)19-26-24(27(31)34-26)18-22(5)7-2/h20-26H,6-19H2,1-5H3,(H,29,30)/t22?,23-,24-,25?,26-/m0/s1
Technical Data
Reference
Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method
Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification
, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses
Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780
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