Enzalutamide Impurity D

Product Description
CAT No.
ALN-E015022
CAS No.
1289942-55-7
Mol. F.
C20H18F4N4O2
Mol. Wt.
422.4
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 4-((1-((4-Cyano-3-(trifluoromethyl)phenyl)amino)-2-methyl-1-oxopropan-2-yl)amino)-2-fluoro-N-methylbenzamide
Smiles : N#CC1=C(C(F)(F)F)C=C(NC(C(C)(C)NC2=CC=C(C(NC)=O)C(F)=C2)=O)C=C1
Inchi : InChI=1S/C17H12F4N4OS/c1-23-15(26)12-5-4-11(7-14(12)18)25-16(27)24-10-3-2-9(8-22)13(6-10)17(19,20)21/h2-7H,1H3,(H,23,26)(H2,24,25,27)
Technical Data
Reference
Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method
Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification
, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443
Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses
Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780
RFQ