Didesmethyl Erlotinib

Product Description
CAT No.
ALN-E018008
CAS No.
183321-84-8
Mol. F.
C20H19N3O4
Mol. Wt.
365.4
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 2,2′-((4-((3-Ethynylphenyl)amino)quinazoline-6,7-diyl)bis(oxy))bis(ethan-1-ol)
Smiles : OCCOC1=C(OCCO)C=C2C(C(NC3=CC(C#C)=CC=C3)=NC=N2)=C1
Inchi : InChI=1S/C22H23N3O5.ClH/c1-4-15-11-16(5-6-19(15)26)25-22-17-12-20(29-9-7-27-2)21(30-10-8-28-3)13-18(17)23-14-24-22;/h1,5-6,11-14,26H,7-10H2,2-3H3,(H,23,24,25);1H
Technical Data
Reference
Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Chris Twelvesa, Joseu00b4 M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Joseu00b4 BaselganEuropean journal of cancer 44 (2008) 419 u2013 426
Development and validation of a stability indicating HPLC method for the quantification of impurities in Erlotinib hydrochloride dosage forms
BabuC1, Narasimha\xa0 RaoK.L1,\xa0 DevannaN1, Suresh Reddy\xa0 K.V.N – Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K
Jinghuan Zhai, Junrui Zhao, Zhenzhen Chen, Changwei Xiao, Xijian Liu, Lijuan Zhang, and Jie Lu
J. Chem. Eng. Data 2017, 62, 1, 516–524 – Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector
RFQ
