Erlotinib Impurity 29

Product Description
CAT No.
ALN-E018046
CAS No.
882172-54-5
Mol. F.
C22H27N3O6
Mol. Wt.
429.5
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 4-((6,7-Bis(2-methoxyethoxy)quinazolin-4-yl)amino)-2-(2-hydroxyethyl)phenol
Smiles : OC1=C(CCO)C=C(C=C1)NC2=NC=NC3=C2C=C(OCCOC)C(OCCOC)=C3
Inchi : InChI=1S/C25H40O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,15-21,23,26H,6,9-14H2,1-5H3/t15-,16-,17-,18+,19+,20-,21-,23-/m0/s1
Technical Data
Reference
Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study
Chris Twelvesa, Joseu00b4 M. Trigob , Rob Jonesc , Flavio De Rosad , Ashok Rakhite , Scott Fettnere , Tonya Wrightc , Joseu00b4 BaselganEuropean journal of cancer 44 (2008) 419 u2013 426
Development and validation of a stability indicating HPLC method for the quantification of impurities in Erlotinib hydrochloride dosage forms
BabuC1, Narasimha\xa0 RaoK.L1,\xa0 DevannaN1, Suresh Reddy\xa0 K.V.N – Solubility Measurement and Correlation of Two Erlotinib Hydrochloride Polymorphs in Alcohols and Ketones from 273.15 to 323.15 K
Jinghuan Zhai, Junrui Zhao, Zhenzhen Chen, Changwei Xiao, Xijian Liu, Lijuan Zhang, and Jie Lu
J. Chem. Eng. Data 2017, 62, 1, 516–524 – Separation and Determination of Process-Related Impurities of Erlotinib Using Reverse-Phase HPLC with a Photo-Diode Array Detector
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