Chemical Name : 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylic acid ;
Smiles : O=C(C1=C(C)N=C(C2=CC=C(O)C(C#N)=C2)S1)O
Synonym : Febuxostat 4-Hydroxy Acid Impurity ;
Technical Data
Reference
HPTLC and Spectrophotometric Estimation of Febuxostat and Diclofenac Potassium in Their Combined Tablets
Fawzi A. El-Yazbi, Omayma A. Amin, Eman I. El-Kimary, Essam F. Khamis, Sameh E. YounisnJournal of Chromatographic Science, Volume 54, Issue 7, 1 August 2016, Pages 1146u20131152
Study of impurity carryover and impurity profile in Febuxostat drug substance by LC-MS/MS technique
Mustakhusen H. Kadivar a, Praveen Kumar Sinhaa, Dharmendra Kushwaha,∗, Pijush Janaa,∗, Hitesh Sharmaa, Atul Bapodra – Journal of Pharmaceutical and Biomedical Analysis 56 (2011) 749–757
Development and Validation of a Stability-Indicating RP-HPLC Method for the Determination of Febuxostat (a Xanthine Oxidase Inhibitor)
