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Fluticasone Impurity 6

Fluticasone Impurity 6

Product Description
CAT No.
ALN-F016054
CAS No.
NA
Mol. F.
C32H31F3O8S
Mol. Wt.
632.6
Stock
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Chemical Name : (6S,9R,10S,11S,13S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-11,17-diyl bis(furan-2-carboxylate)
Smiles : O=C(C1=CC=CO1)O[C@H]2C[C@@]3(C)C(C[C@@H](C)[C@]3(OC(C4=CC=CO4)=O)C(SCF)=O)C5C[C@H](F)C6=CC(C=C[C@]6(C)[C@]52F)=O
Inchi : InChI=1S/C37H63NO5/c1-6-8-10-12-13-14-15-16-20-24-32(43-37(42)34(38-28-39)26-29(3)4)27-35(40)33(25-21-11-9-7-2)36(41)30(5)31-22-18-17-19-23-31/h17-19,22-23,28-30,32-35,40H,6-16,20-21,24-27H2,1-5H3,(H,38,39)/t30-,32+,33+,34+,35+/m1/s1

Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLCu2013NMR spectroscopy and HPLCu2013MS

Nisha Mistry a , Ismail M. Ismail b , Marco S. Smith c , Jeremy K. Nicholson d , John C. LindonnJournal of Pharmaceutical and Biomedical Analysis 16 (1997) 697u2013705

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