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Furosemide Impurity 4

Furosemide Impurity 4

Product Description
CAT No.
ALN-F032013
CAS No.
NA
Mol. F.
C12H10Cl2N2O5S
Mol. Wt.
365.2
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RFQ
Chemical Name : 3,4-Dichloro-2-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid
Smiles : O=C(C1=CC(S(=O)(N)=O)=C(Cl)C(Cl)=C1NCC2=CC=CO2)O
Inchi : InChI=1S/C31H48N2O12/c1-37-8-9-38-10-11-39-12-13-40-14-15-41-16-17-42-18-19-43-20-21-44-25-4-5-31(35)26-22-23-2-3-24(34)28-27(23)30(31,29(25)45-28)6-7-33(26)32-36/h2-3,25-26,29,34-35H,4-22H2,1H3/t25-,26+,29-,30-,31+/m0/s1

A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition Mechanism

E. Kaminska,*,u2020 K. Adrjanowicz,u2021,u00a7 K. Kaminski,u00a7,u2225 P. Wlodarczyk,u22a5 L. Hawelek,u00a7,u22a5 K. Kolodziejczyk,u00a7 M. Tarnacka,u00a7 D. Zakowiecki,# I. Kaczmarczyk-Sedlak,u2020 J. Pilch,u2207 and M. PaluchnMol. Pharmaceutics 2013, 10, 5, 1824u20131835

Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide

,† K. Adrjanowicz,‡,§ K. Kaminski,§,∥ P. Wlodarczyk,⊥ L. Hawelek,§,⊥ K. Kolodziejczyk,§ M. Tarnacka,§ D. Zakowiecki,# I. Kaczmarczyk-Sedlak,† J. Pilch,∇ and M. Paluch – Mol. Pharmaceutics 2013, 10, 5, 1824–1835

Implementation of design of experiments for optimization of forced degradation conditions and development of a stability-indicating method for furosemide

Karolina Adrjanowicz, Kamil Kaminski, Katarzyna Grzybowska, Lukasz Hawelek, Marian Paluch, Irena Gruszka, Daniel Zakowiecki, Wieslaw Sawicki, Przemyslaw Lepek, Wojciech Kamysz & Lukasz Guzik – Pharmaceutical Research volume 28, pages3220–3236(2011)

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