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Furosemide Impurity 8

Furosemide Impurity 8

Product Description
CAT No.
ALN-F032017
CAS No.
1579293-74-5
Mol. F.
C12H11ClN2O7S
Mol. Wt.
362.7
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RFQ
Chemical Name : 2-((4-Carboxy-2-oxobut-3-en-1-yl)amino)-4-chloro-5-sulfamoylbenzoic acid
Smiles : O=C(O)C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC(/C=C/C(O)=O)=O
Inchi : InChI=1/C12H13ClN2O6S/c13-9-8(22(14,19)20)4-7(12(17)18)10(11(9)16)15-5-6-2-1-3-21-6/h1-4,7,9-10,15H,5H2,(H,17,18)(H2,14,19,20)

A New Way of Stabilization of Furosemide upon Cryogenic Grinding by Using Acylated Saccharides Matrices. The Role of Hydrogen Bonds in Decomposition Mechanism

E. Kaminska,*,u2020 K. Adrjanowicz,u2021,u00a7 K. Kaminski,u00a7,u2225 P. Wlodarczyk,u22a5 L. Hawelek,u00a7,u22a5 K. Kolodziejczyk,u00a7 M. Tarnacka,u00a7 D. Zakowiecki,# I. Kaczmarczyk-Sedlak,u2020 J. Pilch,u2207 and M. PaluchnMol. Pharmaceutics 2013, 10, 5, 1824u20131835

Effect of Cryogrinding on Chemical Stability of the Sparingly Water-Soluble Drug Furosemide

,† K. Adrjanowicz,‡,§ K. Kaminski,§,∥ P. Wlodarczyk,⊥ L. Hawelek,§,⊥ K. Kolodziejczyk,§ M. Tarnacka,§ D. Zakowiecki,# I. Kaczmarczyk-Sedlak,† J. Pilch,∇ and M. Paluch – Mol. Pharmaceutics 2013, 10, 5, 1824–1835

Implementation of design of experiments for optimization of forced degradation conditions and development of a stability-indicating method for furosemide

Karolina Adrjanowicz, Kamil Kaminski, Katarzyna Grzybowska, Lukasz Hawelek, Marian Paluch, Irena Gruszka, Daniel Zakowiecki, Wieslaw Sawicki, Przemyslaw Lepek, Wojciech Kamysz & Lukasz Guzik – Pharmaceutical Research volume 28, pages3220–3236(2011)

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