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3-Deschloro-3,4-Difluoro Gefitinib

3-Deschloro-3,4-Difluoro Gefitinib

Product Description
CAT No.
ALN-G018032
CAS No.
184475-50-1
Mol. F.
C22H24F2N4O3
Mol. Wt.
430.5
Stock
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Chemical Name : N-(3,4-difluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine
Smiles : COC(C=C(N=CN=C1NC2=CC(F)=C(F)C=C2)C1=C3)=C3OCCCN4CCOCC4
Inchi : InChI=1S/C21H23ClO7/c1-2-28-13-6-3-11(4-7-13)17(24)14-9-12(5-8-15(14)22)21-20(27)19(26)18(25)16(10-23)29-21/h3-9,16,18-21,23,25-27H,2,10H2,1H3/t16-,18-,19+,20-,21+/m1/s1
Synonym : 4-Quinazolinamine

Identification, characterization and HPLC quantification of formulation-related impurities of honokiol, an antitumor natural drug candidate in clinical trials

Wenshuang Wu 1,2, # , Ming-Hai Tang2, # , Huan Tang 2 , Kai Chen 2,3 , Jie Fu 4 , Lun Wang 2,3 , Lin-Lin Xue 2 , Aihua Peng 2 , Haoyu Ye 2, 4* , Li-Juan ChennJournal of Pharmaceutical and Biomedical Analysis Volume 153, 10 May 2018, Pages 186-192

Separation and Estimation of Process-Related Impurities of Gefitinib by Reverse-Phase High-Performance Liquid Chromatography

, Li-Juan Chen – Journal of Pharmaceutical and Biomedical Analysis Volume 153, 10 May 2018, Pages 186-192
Karunakara A. Chandrashekara, Aparna Udupi, Chandrasekara G. Reddy – Journal of Chromatographic Science, Volume 52, Issue 8, September 2014, Pages 799–805

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