Griseofulvin EP Impurity A

Product Description
CAT No.
ALN-G003002
CAS No.
469-54-5
Mol. F.
C16H15ClO6
Mol. Wt.
338.7
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : (1′S,6′R)-7-Chloro-4,6-dimethoxy-6′-methyl-3H-spiro[1-benzofuran-2,1′-cyclohexane]-2′,3,4′-trione, (as per EP)
Smiles : O=C(CC1=O)C[C@@H](C)[C@@]21OC3=C(Cl)C(OC)=CC(OC)=C3C2=O
Inchi : InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
Synonym : Griseofulvic acid
Technical Data
Reference
Development and validation of a reversed phase liquid chromatographic method for analysis of griseofulvin and impurities
Getu Kahsaya, Aremu Olajire Adegoke b, Ann Van Schepdael a, Erwin AdamsnJournal of Pharmaceutical and Biomedical Analysis 80 (2013) 9u201317
Thermodynamics, Molecular Mobility and Crystallization Kinetics of Amorphous Griseofulvin
Deliang Zhou,Geoff G. Z. Zhang, Devalina Law,David J. W. Grant, and Eric A. Schmitt – Mol. Pharmaceutics 2008, 5, 6, 927–936
In Vitro additive effect on griseofulvin and terbinafine combinations against multidrug-resistant dermatophytes
Aline Jacobi Dalla Lana, Bruna Pippi, Anderson Ramos Carvalho, Renata Cougo Moraes, Samuel Kaiser, George Gonzalez Ortega, Alexandre Meneghello Fuentefria, Gustavo Pozza Silveira – Braz. J. Pharm. Sci. vol.54 no.2 São Paulo\xa0 2018\xa0 Epub July 26, 2018
RFQ