Hydroxychloroquine EP Impurity A

Product Description
CAT No.
ALN-H004010
CAS No.
1449223-88-4
Mol. F.
C18H26ClN3O2
Mol. Wt.
351.9
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 4-[(7-chloroquinolin-4-yl)amino]-N-ethyl-N-(hydroxyethyl)pentan-1-amine N-oxide (as per EP)
Smiles : ClC1=CC=C(C(NC(CCC[N+](CC)([O-])CCO)C)=CC=N2)C2=C1
Inchi : InChI=1/C26H27Cl2N3O/c1-18(30-24-6-2-5-19-16-20(27)7-9-22(19)24)4-3-13-31(14-15-32)26-11-12-29-25-17-21(28)8-10-23(25)26/h2,5-12,16-18,30,32H,3-4,13-15H2,1H3
Synonym : Hydroxychloroquine N-Oxide
Technical Data
Reference
Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR
By Dongre, Vaijanath G.; Ghugare, Pradeep D.; Karmuse, Pravin; Singh, Dharmendra; Jadhav, Atul; Kumar, AshoknFrom Journal of Pharmaceutical and Biomedical Analysis (2009), 49(4), 873-879
Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers
By Brocks, Dion R.; Pasutto, Franco M.; Jamali, Fakhreddin – From Journal of Chromatography, Biomedical Applications (1992), 581(1), 83-92
Estimation of plasma hydroxychloroquine by high-performance liquid chromatography with ultraviolet detection
By Morris, Raymond G. – From Journal of Chromatography, Biomedical Applications (1985), 338(2), 422-7
RFQ