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Hydroxyzine Impurity 2

Hydroxyzine Impurity 2

Product Description
CAT No.
ALN-H014007
CAS No.
346451-15-8
Mol. F.
C30H28Cl2N2
Mol. Wt.
487.5
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RFQ
Chemical Name : 1,4-Bis((4-chlorophenyl)(phenyl)methyl)piperazine
Smiles : ClC1=CC=C(C(N2CCN(C(C3=CC=CC=C3)C4=CC=C(Cl)C=C4)CC2)C5=CC=CC=C5)C=C1
Inchi : InChI=1S/C8H18N2O2.2ClH/c11-6-8-12-7-5-10-3-1-9-2-4-10;;/h9,11H,1-8H2;2*1H
Synonym : Cetirizine Dimer Impurity (USP)

Method for the control of known impurities in hydroxyzine hydrochloride

D. Simpson a’*, G.G. Skellern a, J.H.McB. Miller bnJournal of Pharmaceutical and Biomedical Analysis 14 (1996) 1371-1375

A High Performance Liquid Chromatography Method for Determination of Hydroxyzine Hydrochloride in Syrup

, G.G. Skellern a, J.H.McB. Miller b – Journal of Pharmaceutical and Biomedical Analysis 14 (1996) 1371-1375″, A.f. brandão 1,2
, luiz g.b. nascimento 1, hudson c. polonini 1, roberta g. fonseca 2, gabriela montesano 1, urias p. vaz 1, nádia r.b. raposo 1, lívia n. grossi 2 & anderson o. ferreira – Lat. Am. J. Pharm. 30 (9): 1798-1802 (2011)

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