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Ivabradine 12-Isomer Impurity

Ivabradine 12-Isomer Impurity

Product Description
CAT No.
ALN-I014060
CAS No.
NA
Mol. F.
C28H37NO5 : HCl
Mol. Wt.
467.6 : 36.5
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RFQ
Chemical Name : 7-(3-((((R)-3,4-Dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-2,3-dimethoxy-5,7,8,9-tetrahydro-6H-benzo[7]annulen-6-one hydrochloride
Smiles : COC1=CC2=C(CC(C(CCCN(C)C[C@H]3C(C=C(OC)C(OC)=C4)=C4C3)CC2)=O)C=C1OC.Cl
Inchi : InChI=1S/C22H29NO6/c1-25-17-8-13-6-7-23-21(15(13)11-18(17)26-2)16(12-24)14-9-19(27-3)22(29-5)20(10-14)28-4/h8-11,16,21,23-24H,6-7,12H2,1-5H3/t16-,21+/m0/s1

Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities

Piotr Pikul,1 Marzena Jamru00f3giewicz,1,* Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir CiuranFront Pharmacol. 2016; 7: 117.

Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic mode

Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir Ciura – Front Pharmacol. 2016; 7: 117.

Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4 acid hydrolysis

ElekFerenczabBélaKovácsabFranciscBodaaMohammadhassanForoughbakhshfasaeicÉva KatalinKelemenbGerg?TóthcZoltán-IstvánSzabó – Journal of Pharmaceutical and Biomedical Analysis Volume 177, 5 January 2020, 112851

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