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Ivabradine Dimer Impurity (HCl salt)

Ivabradine Dimer Impurity (HCl salt)

Product Description
CAT No.
ALN-I014031
CAS No.
NA
Mol. F.
C41H53N3O8 : HCl
Mol. Wt.
715.9 : 36.5
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RFQ
Chemical Name : (S)-3,3′-((((3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)methyl)azanediyl)bis(propane-3,1-diyl))bis(7,8-dimethoxy-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one) hydrochloride
Smiles : O=C1CC2=C(C=C(OC)C(OC)=C2)CCN1CCCN(CCCN3CCC4=CC(OC)=C(OC)C=C4CC3=O)C[C@@H]5C6=CC(OC)=C(OC)C=C6C5.Cl
Inchi : InChI=1S/C25H32N4O6/c1-27(2)13-9-14(28(3)4)20(30)16-11(13)7-10-8-12-17(22(32)15(10)21(16)31)23(33)18(25(26)35)24(34)19(12)29(5)6/h9-10,12,17,19,30,32,34H,7-8H2,1-6H3,(H2,26,35)/t10-,12+,17+,19-/m0/s1
Synonym : N-(Demethyl)diithabradine

Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities

Piotr Pikul,1 Marzena Jamru00f3giewicz,1,* Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir CiuranFront Pharmacol. 2016; 7: 117.

Simultaneous determination of chiral and achiral impurities of ivabradine on a cellulose tris(3-chloro-4-methylphenylcarbamate) chiral column using polar organic mode

Joanna Nowakowska,1 Weronika Hewelt-Belka,2,3 and Krzesimir Ciura – Front Pharmacol. 2016; 7: 117.

Characterization of degradation products of Ivabradine by LC-HR-MS/MS: a typical case of exhibition of different degradation behaviour in HCl and H2SO4 acid hydrolysis

ElekFerenczabBélaKovácsabFranciscBodaaMohammadhassanForoughbakhshfasaeicÉva KatalinKelemenbGerg?TóthcZoltán-IstvánSzabó – Journal of Pharmaceutical and Biomedical Analysis Volume 177, 5 January 2020, 112851

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