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Ketoconazole Impurity 15

Ketoconazole Impurity 15

Product Description
CAT No.
ALN-K001026
CAS No.
NA
Mol. F.
C26H28Cl2N4O7S
Mol. Wt.
611.5
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Chemical Name : 2-(((2R,4S)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)-5-(4-acetylpiperazin-1-yl)phenyl hydrogen sulfite
Smiles : CC(N1CCN(C2=CC(OS(O)=O)=C(OC[C@@H]3O[C@@](CN4C=NC=C4)(C5=CC=C(Cl)C=C5Cl)OC3)C=C2)CC1)=O
Inchi : InChI=1S/C12H8N4/c1-3-9(7-13-5-1)12-15-8-10-4-2-6-14-11(10)16-12/h1-8H
Synonym : Ketoconazole Bisulfide

Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresisu2013mass spectrometry

Maru00b4u0131a Castro-Puyana a, Carmen Garcu00b4u0131a-Ruiz a, Alejandro Cifuentes b, Antonio L. Crego a, Maria Luisa MarinanJournal of Chromatography A, 1114 (2006) 170u2013177

Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor

Aneta Grycová , Aneta Do?i?áková 1, Zden?k Dvo?ák – Toxicol Lett . 2015 Dec 3;239(2):67-72

Ion-pairing liquid chromatographic method determination of ketoconazole and stress degradation in pharmaceutical formulations with fluorescence detection

Wisanu Thongchai – Brazilian Journal of Pharmaceutical Sciences Sci. vol.56

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