Ketoconazole Impurity 2

Product Description
CAT No.
ALN-K001012
CAS No.
NA
Mol. F.
C26H26Cl2N4O4
Mol. Wt.
529.4
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 1-(4-(2-(1-(1,3-Dioxolan-4-yl)-2-(1H-imidazol-1-yl)ethoxy)-2′,4′-dichloro-[1,1′-biphenyl]-4-yl)-3,4-dihydropyrazin-1(2H)-yl)ethan-1-one
Smiles : ClC1=CC(Cl)=CC=C1C2=CC=C(N3CCN(C(C)=O)C=C3)C=C2OC(CN4C=CN=C4)C5OCOC5
Technical Data
Reference
Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresisu2013mass spectrometry
Maru00b4u0131a Castro-Puyana a, Carmen Garcu00b4u0131a-Ruiz a, Alejandro Cifuentes b, Antonio L. Crego a, Maria Luisa MarinanJournal of Chromatography A, 1114 (2006) 170u2013177
Impurities contained in antifungal drug ketoconazole are potent activators of human aryl hydrocarbon receptor
Aneta Grycová , Aneta Do?i?áková 1, Zden?k Dvo?ák – Toxicol Lett . 2015 Dec 3;239(2):67-72
Ion-pairing liquid chromatographic method determination of ketoconazole and stress degradation in pharmaceutical formulations with fluorescence detection
Wisanu Thongchai – Brazilian Journal of Pharmaceutical Sciences Sci. vol.56
RFQ