Ledipasvir Impurity-9
 
		Product Description
CAT No.
				
									ALN-L010019								
				CAS No.
				
									NA								
				Mol. F.
				
									C18H23N3O2								
				Mol. Wt.
				
									313.4								
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							Product Overview
			
						
									Chemical Name : Tert-butyl (1R,3R,4S)-3-(1H-benzo[d]imidazol-2-yl)-2-azabicyclo[2.2.1]heptane-2-carboxylate								
				
									Smiles : CC(C)(C)OC(N1[C@@H](C2=NC3=CC=CC=C3N2)[C@@]4([H])CC[C@]1([H])C4)=O								
				
									Inchi : InChI=1S/C18H23N3O2/c1-18(2,3)23-17(22)21-12-9-8-11(10-12)15(21)16-19-13-6-4-5-7-14(13)20-16/h4-7,11-12,15H,8-10H2,1-3H3,(H,19,20)/t11-,12+,15-/m1/s1								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Insights into the Dissolution Behavior of Ledipasvir-Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions
									Chailu Que, Xiaochun Lou, Dmitry Y. Zemlyanov, Huaping Mo, Anura S. Indulkar, Yi Gao, Geoff G.Z. Zhang, and Lynne S. TaylornMol. Pharmaceutics 2019, 16, 12, 5054u20135067								
				A green stability-indicating RP-HPLC-UV method using factorial design for determination of ribavirin, sofosbuvir and ledipasvir: Application to average content, acid degradation kinetics and in vitro drug interactions study
									Hanan I.EL-ShorbagyacFawziElsebaeiaSherin F.HammadbAmina M.El-Brashy – Microchemical Journal Volume 158, November 2020, 105251 								
				Simultaneous chromatographic analysis of Sofosbuvir/Ledipasvir in their combined dosage form: an application to green analytical chemistry
									Ahmed Hemdan & Maya S. Eissa – Journal of Analytical Science and Technology volume 10, Article number: 39 (2019) 								
				
							
							
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