Lenalidomide N-Hydroxy Impurity

Product Description
CAT No.
ALN-L031006
CAS No.
2717380-87-3
Mol. F.
C13H13N3O4
Mol. Wt.
275.3
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Technical Data
Reference
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Product Overview
Chemical Name : 3-(4-(Hydroxyamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Smiles : ONC1=CC=CC2=C1CN(C3C(NC(CC3)=O)=O)C2=O
Inchi : InChI=1S/C19H23N3O8/c20-10-3-1-2-8-9(10)6-21(17(8)28)11-4-5-13(24)22(18(11)29)19-16(27)15(26)14(25)12(7-23)30-19/h1-3,11-12,14-16,19,23,25-27H,4-7,20H2/t11?,12-,14-,15+,16-,19-/m0/s1
Technical Data
Reference
Determination of possible potential genotoxic impurities in lenalidomide drug substance by simple RP-HPLC method
By Gaddam, Kishore; Kanne, Shanker; Gundala, Trivikram Reddy; Mamilla, Yogeshwar Reddy; Chinna, Gangi Reddy NallagondunFrom Asian Journal of Chemistry (2020), 32(12), 2965-2970
Development and validation of stability-indicating RP-HPLC method for the estimation of lenalidomide and its impurities in oral solid dosage form
By Prasad, Somana Siva; Mohan, G. V. Krishna; Babu, A. Naga – From Oriental Journal of Chemistry (2019), 35(1), 140-149
Simultaneous quantification of lenalidomide, ibrutinib and its active metabolite PCI-45227 in rat plasma by LC-MS/MS: Application to a pharmacokinetic study
By Veeraraghavan, Sridhar; Viswanadha, Srikant; Thappali, Satheeshmanikandan; Govindarajulu, Babu; Vakkalanka, Swaroopkumar; Rangasamy, Manivannan – From Journal of Pharmaceutical and Biomedical Analysis (2015), 107, 151-158
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