Lopinavir EP Impurity B

CAT No.

ALN-L008003

CAS No.

Mol. F.

C28H38N4O4

Mol. Wt.

494.6

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Product Overview

Technical Data

Reference

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Product Overview

Chemical Name : (2S)-N-[(1S,3S,4S)-1-benzyl-4-(formylamino)-3-hydroxy-5-phenylpentyl]-3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide (as per EP) ; (S)-N-[(2S,4S,5S)-5-Formamido-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-[2-oxotetrahydropyrimidin-1(2H)-yl]butanamide (as per USP)

Smiles : CC(C)[C@H](N1CCCNC1=O)C(N[C@@H](CC2=CC=CC=C2)C[C@H](O)[C@@H](NC=O)CC3=CC=CC=C3)=O

Inchi : InChI=1S/C37H48N4O5/c1-25(2)34(41-20-12-19-38-37(41)45)36(44)39-30(21-28-15-7-5-8-16-28)23-32(42)31(22-29-17-9-6-10-18-29)40-33(43)24-46-35-26(3)13-11-14-27(35)4/h5-11,13-18,25,30-32,34,42H,12,19-24H2,1-4H3,(H,38,45)(H,39,44)(H,40,43)/t30-,31-,32-,34-/m0/s1

Synonym : Lopinavir N-Formylaminoalcohol (USP)

Technical Data

Reference

By Srinivas, L.; Jain, NeelunFrom International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 786-792

By Jadhav, Sarika R.; Alhat, Hemant P.; Joshi, Suhas – From International Research Journal of Pharmacy (2018), 9(8), 57-62

By Bhavyasri, Khagga; Balaram, V. Murali; Nageswarao, R.; Rambabu, D.; Ajitha, M. – From International Journal of Chemical Sciences (2015), 13(1), 551-562

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