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Losartan Impurity 33

Losartan Impurity 33

Product Description
CAT No.
ALN-L028071
CAS No.
114798-27-5
Mol. F.
C22H23ClN2O3
Mol. Wt.
398.9
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Chemical Name : 4′-((2-butyl-4-chloro-5-(hydroxymethyl)-1H-imidazol-1-yl)methyl)-[1,1′-biphenyl]-2-carboxylic acid
Smiles : OCC1=C(Cl)N=C(CCCC)N1CC2=CC=C(C(C=CC=C3)=C3C(O)=O)C=C2
Inchi : InChI=1S/C22H24N2O3/c1-2-3-8-21-23-13-18(15-25)24(21)14-16-9-11-17(12-10-16)19-6-4-5-7-20(19)22(26)27/h4-7,9-13,25H,2-3,8,14-15H2,1H3,(H,26,27)

Development and validation of a stability-indicating HPLC method for the simultaneous determination of Losartan potassium, hydrochlorothiazide, and their degradation products

Deanne L. Hertzog a,*, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. ReednJournal of Pharmaceutical and Biomedical Analysis 30 (2002) 747u2013760

An Efficient, Commercially Viable, and Safe Process for Preparation of Losartan Potassium, an Angiotensin II Receptor Antagonist

, Jennifer Finnegan McCafferty b , Xueguang Fang b , R. Jeffrey Tyrrell c , Robert A. Reed – Journal of Pharmaceutical and Biomedical Analysis 30 (2002) 747–760
Suri Babu Madasu,†,‡ N. A. Vekariya,

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