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Lumefantrine Benzylidine Impurity

Lumefantrine Benzylidine Impurity

Product Description
CAT No.
ALN-L058019
CAS No.
1276121-35-7
Mol. F.
C30H33Cl2NO
Mol. Wt.
494.5
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Chemical Name : (Z)-1-(9-benzylidene-2,7-dichloro-9H-fluoren-4-yl)-2-(dibutylamino)ethan-1-ol
Smiles : CCCCN(CC(O)C1=CC(Cl)=CC(/C2=C\C3=CC=CC=C3)=C1C4=C2C=C(Cl)C=C4)CCCC
Inchi : InChI=1S/C53H87NO19.C4H6O6/c1-16-38-36(26-65-52-49(64-15)48(63-14)44(60)31(7)67-52)22-28(4)17-18-37(57)29(5)23-35(19-20-55)46(30(6)39(69-34(10)56)24-41(59)70-38)73-51-45(61)43(54(12)13)47(32(8)68-51)72-42-25-53(11,62)50(33(9)66-42)71-40(58)21-27(2)3;5-1(3(7)8)2(6)4(9)10/h17-18,20,22,27,29-33,35-36,38-39,42-52,60-62H,16,19,21,23-26H2,1-15H3;1-2,5-6H,(H,7,8)(H,9,10)/b18-17+,28-22+;/t29-,30+,31-,32-,33+,35?,36-,38-,39?,42+,43-,44-,45-,46-,47-,48-,49-,50+,51+,52-,53-;1-,2-/m11/s1

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine

Mathieu Verbeken1u2020 , Sultan Suleman1,3u2020 , Bram Baert1 , Elien Vangheluwe1 , Sylvia Van Dorpe1 , Christian Burvenich2 , Luc Duchateau2 , Frans H Jansen4 , Bart De SpiegeleernVerbeken et al. Malaria Journal 2011, 10:51 Page 2 of 9

Analytical Method Development and Validation for Estimation of Lumifantrine in Pharmaceutical Dosage Forms by HPLC

Naveen S Kotur

A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study

1 ,Singaravel Sivasamy2 , S.Srinivasan – J. Pharm. Sci. & Res. Vol.4(1), 2012,1672-1675

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