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Lumefantrine Epoxy Derivative Impurity

Lumefantrine Epoxy Derivative Impurity

Product Description
CAT No.
ALN-L058006
CAS No.
252990-29-7
Mol. F.
C22H13Cl3O
Mol. Wt.
399.7
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RFQ
Chemical Name : (E,Z)-9-(4-Chlorophenyl)methylene-5-oxiranyl-2,7-dichlorofluorene
Smiles : ClC1=CC=C(C=C1)/C=C2C3=C(C4=C\2C=C(Cl)C=C4)C(C5OC5)=CC(Cl)=C3
Inchi : InChI=1S/C11H23NO2.ClH/c1-8(2)5-10(7-12)6-11(13)14-9(3)4;/h8-10H,5-7,12H2,1-4H3;1H/t10-;/m0./s1

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine

Mathieu Verbeken1u2020 , Sultan Suleman1,3u2020 , Bram Baert1 , Elien Vangheluwe1 , Sylvia Van Dorpe1 , Christian Burvenich2 , Luc Duchateau2 , Frans H Jansen4 , Bart De SpiegeleernVerbeken et al. Malaria Journal 2011, 10:51 Page 2 of 9

Analytical Method Development and Validation for Estimation of Lumifantrine in Pharmaceutical Dosage Forms by HPLC

Naveen S Kotur

A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study

1 ,Singaravel Sivasamy2 , S.Srinivasan – J. Pharm. Sci. & Res. Vol.4(1), 2012,1672-1675

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